
1.个人简介:
胡小红,博士,教授,一直从事生物医用高分子的研究。2017年美国俄亥俄州立大学访问研究。为江苏高校“青蓝工程”中青年学术带头人(2017-2020),江苏省六大人才高峰人才(2016-2020),江苏高校“青蓝工程”优秀青年骨干教师(2012-2016),江苏省333人才(2013-2015)。
2.学术任职与学术荣誉
(1)International Journal of Polymer Science 客座编辑
(2)中国生物医学工程学会组织工程与再生医学分会第三届理事会委员
3.科学研究
长期从事生物医用高分子材料研究,近年来一直围绕用于药物传递的载体材料,生物降解和生物活性水凝胶的结构设计、制备方法和性能研究等方面开展研究,以第一或通讯发表40余篇论文,10余个发明专利获授权,主持国家自然科学基金1项,江苏省自然科学基金2项,横向课题2项,获江苏省高等学校教育科学研究成果奖自然科学二等奖2项(第一和第四)、中国医药教育协会科技创新二等奖1项(第一)。
4. 教育教学
主讲高分子化学、复合材料综合实训,指导江苏省本科优秀毕业论文三等奖2篇,二等奖1篇,挑战杯省赛3等奖1项,二等奖1项,各类各级学科竞赛和大学生创新创业项目若干。
5. 研究生招生方向
高分子材料或复合材料方向
6. 主要承担项目
u 功能复合材料创新团队,金陵科技学院校创新团队,2019-2020, 经费:10万
u 江苏省自然科学基金(面上研究项目,BK20171113):石墨烯/多糖水凝胶促进角膜再生的研究,2017-2020,经费:10万
u 六大人才高峰项目(C类-教育,JY-071):光动力与化疗联合治疗用多重响应型药物载体的研究,2016-2019,经费:4万
u 横向课题:阴极电泳漆的检测,2014,经费:19万
u 国家自然科学基金(青年基金,51103066):具有仿生特性的角膜接触镜眼药载体的构建及其控释性能的研究,2012-2014,经费:25万;
u 江苏省自然科学基金(面上研究项目,BK2011091):抗肿瘤石墨烯/水凝胶复合药物载体的制备与研究,2012-2014,经费:10万;
u 金陵科技学院博士启动基金:长期眼药缓释用仿生角膜接触镜材料的研制,2010-2012,经费:3万;
u 横向课题:水凝胶敷料的研制,2011,经费:5万;
7. 主要文章及专利
发表学术论文:
1. Xiaohong Hu*, Weiwei Jin, Haitao Zhang, Qinyu Qing, Juan Pang. Development of visible-light driven photo-switching copolymers with pH indicating performance. International Journal of Polymer Analysis and Characterization. 2023, 28 (3), 256-268.
2. Xiaoxia Lin, Haitao Zhang, Yuqing Qin and Xiaohong Hu*. Design and Fabrication of Photo-Responsive Hydrogel for the Application of Functional Contact Lens. Front. Mater. 2021, 8, ID:680359.
3. Juan Pang, Xincheng Mao, Jialin Xu, Xiang Zhao, Jingyang Kong, Xiaohong Hu*. Design, synthesis and investigation of a visible-light driven photo-switching macromolecule. RSC Adv., 2020, 10, 35164–35173.
4. Pin Chen, Jingyang Kong, Xin Wang, Weiye Ma, Xia Yang, Yuqing Qin, Xiaohong Hu*. Development of light responsive poly(γ-benzyl-L-glutamate) as photo switches by one-step NCA method. Front. Chem. 2020, 8, Article ID: 591.
5. Juan Pang, Li Shu, Ming Li, Xiaohong Hu*. Theoretical insights into a colorimetric azo-based probe to detect copper ions. RSC Adv., 2020, 10, 23196-23202.
6. Juan Pang, Jingyang Kong, Jialing Xu, Xincheng Mao and Xiaohong Hu*. Synthesis and Investigation of Macromolecular Photoswitches. Frontiers in Materials. 2020, 7, Article ID: 120.
7. Pin Chen, Xin Wang, Jingyang Kong, and Xiaohong Hu* A Facile Route to Fabricate CS/GO Composite Film for the Application of Therapeutic Contact Lenses. Advances in Materials Science and Engineering 2020, Article ID 8476025
8. Juan Pang, Ziyu Gao, Huaping Tan, Xincheng Mao, Jialing Xu, Jingyang Kong and Xiaohong Hu*. Fabrication, Investigation, and Application of Light-Responsive Self-Assembled Nanoparticles. Front. Chem. 2019, Article ID: 620.
9. Xiaohong Hu*, Ziyu Gao, Huaping Tan, Huiming Wang, Xincheng Mao, Juan Pang. An Injectable Hyaluronic Acid-Based Composite Hydrogel by DA Click Chemistry With pH Sensitive Nanoparticle for Biomedical Application. Front. Chem. 2019, Article ID: 477.
10. Juan Pang, Ziyu Gao, Huaping Tan, Xincheng Mao, Huiming Wang, Xiaohong Hu*. Design, Synthesis, Investigation, and Application of a Macromolecule Photoswitch. Front. Chem., 2019, Article ID: 86.
11. Xiaohong Hu*, Ziyu Gao, Huaping Tan, Huiming Wang. A pH-Responsive Multifunctional Nanocarrier in the Application of Chemo-Photodynamic Therapy. Journal of Nanomaterials 2019, Article ID: 3898564.
12. Yuanfeng Ye, Xincheng Mao, Jialing Xu, Jingyang Kong, Xiaohong Hu*. Functional Graphene Oxide Nanocarriers for Drug Delivery. International Journal of Polymer Science 2019, Article ID: 8453493.
13. Xin Wang, Pin Chen, Xiaohong Hu* A new route to fabricate multifunctional and multistage composite nanoparticle. International Journal of Polymer Science 2018, Article ID: 3035629.
14. Juan Pang, Ziyu Gao, Long Zhang, Huiming Wang, Xiaohong Hu* Synthesis and Characterization of Photoresponsive Macromolecule for Biomedical Application. Frontiers in Chemistry. 2018, 6, Article ID 217.
15. Xin Wang, Ziyu Gao, Long Zhang, Huiming Wang, Xiaohong Hu*. A Magnetic and pH-Sensitive Composite Nanoparticle for Drug Delivery. Journal of Nanomaterials. 2018, Article ID:1506342.
16. Xiaohong Hu*, Shangneng Chen, Xiao Gong, Ziyu Gao, Xin Wang, Pin Chen. Synthesis and preparation of biocompatible and pH-responsive cyclodextrin-based nanoparticle. Journal of Nanoparticle Research. 2017, 19:109.
17. Q. Lin, X. H. Hu*. Synthesis and biomedical application of polymer vesicles composite hydrogels. Materials Technology: Advanced Performance Materials. 2017, 32(4): 225-230.
18. Xiaohong Hu*, Huaping Tan, Lingyun Hao*. Functional hydrogel contact lens for drug delivery in the application of oculopathy therapy. Journal of the Mechanical Behavior of Biomedical Materials, 2016, 64, 43–52.
19. Xiaohong Hu, Xiao Gong*, A new route to fabricate biocompatible hydrogels with controlled drug delivery behavior. Journal of Colloid and Interface Science, 2016, 470:62–70.
20. Xiaohong Hu*, Huaping Tan, Xin Wang, Pin Chen . Surface functionalization of hydrogel by thiol-yne click chemistry for drug delivery. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2016, 489: 297-304
21. Xiaohong Hu*, Huaping Tan, Pin Chen, Xin Wang, Juan Pang, Polymer Micelles Laden Hydrogel Contact Lenses for Ophthalmic Drug Delivery. Journal of Nanoscience and Nanotechnology. 2016, 16, 5480–5488.
22. Yuanfeng Ye, Xiaohong Hu*. A pH-Sensitive Injectable Nanoparticle Composite Hydrogel for Anticancer Drug Delivery, Journal of Nanomaterials, 2016, Article ID 9816461.
23. Pin Chen, Xin Wang, Yan Dong, Xiaohong Hu*, Development of a Layer-by-Layer Assembled Film on Hydrogel for Ocular Drug Delivery. International Journal of Polymer Science 2015, Article ID: 535092.
24. P. Chen, X. Wang, J. Pang, Y. Dong, X. Ma and X. Hu*. Drug release behaviour from drug loaded LBL multilayer on hydrogel. Mater Technol: Adv Perform Mater, 2015, 30(3): 159-161.
25. Ming Fan, Jingxuan Yan, Huaping Tan,* Dandan Ben, Qiuling He, Zhongwei Huang, Xiaohong Hu*. Nanostructured Gel Scaffolds for Osteogenesis through Biological Assembly of Biopolymers via Specific Nucleobase Pairing. Macromol. Biosci. 2014, 14: 1521–1527.
26. P. Chen, X. Wang, G. Wang, Y. R. Duo, X.Y. Zhang, X. H. Hu* and X. J. Zhang. Double network self-healing graphene hydrogel by two step method for anticancer drug delivery. Mater Technol: Adv Perform Mater, 2014,29(4):210-213.
27. X. H. Hu*, G. J. Zhang, H. P. Tan, D. Li, X. Y. Chen, Y. S. Zhang. Synthesis and surface modification of chitosan containing hydrogel for ophthalmic drug delivery. Mater Technol: Adv Perform Mater,2014, 29(3): 144-151.
28. Xiaohong Hu*, Dan Li, Huaping Tan, Chengbin Pan, Xiuxia Chen. Injectable Graphene Oxide/Graphene Composite Supramolecular Hydrogel for Delivery of Anti-Cancer Drugs. J Macromol Sci A, 2014, 51(4): 378–384.
29. X. H. Hu*, H. P. Tan, D. Li, M. Y. Gu. Surface functionalisation of contact lenses by CS/HA multilayer film to improve its propeties and deliver drugs. Mater Technol: Adv Perform Mater, 2014, 29(1):8-13.
30. Xiaohong Hu*, Xiuxia Chen, Huaping Tan, Dan Li, Yuansheng Zhang, Chengbin Pan. Preparation of Biocompatible Graphene Oxide Composite Hydrogel to Deliver Ophthalmic Drugs. J Macromol Sci A 2013, 50(12):1201-1208.
31. Xiaohong Hu*, Jie Qiu, Huaping Tan, Dan Li, Xiaohan Ma. Synthesis and Characterization of Cyclodextrin containing Hydrogel for Ophthalmic Drugs Delivery. J Macromol Sci A, 2013, 50(9): 983-990.
32. Xiaohong Hu*, Xiaohan Ma, Huaping Tan, Dan Li. Preparation of water-soluble and biocompatible graphene. Micro & Nano Letters, 2013, 8(6): 277-279.
33. X. H. Hu*, D. Li. Facile way to synthesise hydrogel contact lenses with good performance for ophthalmic drug delivery. Mater Technol: Adv Perform Mater, 2013, 28(4), 192-198.
34. Xiaohong Hu*, Lingyun Hao, Huaiqing Wang, Xiaoli Yang, Guojun Zhang, Guoyu Wang, Xiao Zhang. Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs. International Journal of Polymer Science. doi:10.1155/2011/814163.
35. Xiaohong Hu, Dan Li, Feng Zhou, Changyou Gao*. On the structure alteration of crosslinkable gelatin coupled with methacrylic acid and its hydrogel e-Polymers 2012, no. 014.
36. Xiaohong Hu, Dan Li, Changyou Gao*. Chemically cross-linked chitosan hydrogel loaded with gelatin for chondrocyte encapsulation. Biotechnology Journal. 2011, 6(11):1388-96.
37. Xiaohong Hu, Dan Li, Feng Zhou, Changyou Gao*.Biological hydrogel synthesized from hyaluronic acid, gelatin and chondroitin sulfate by click chemistry. acta biomaterialia. 2011, 7:1618–1626.
38. Xiaohong Hu, Lie Ma, Chengchao Wang, Changyou Gao*. Gelatin hydrogel prepared by photo-initiated polymerization and loaded with TGF-b1 for cartilage tissue engineering. Macromolecular Bioscience. 2009, 9:1194-1201.
39.胡小红,朱旸,高长有*. 用于软骨修复的水凝胶研究进展. 化学进展. 2009, 10:2165-2176.
40. Xiaohong Hu, Changyou Gao*. Photoinitiating Polymerization to Prepare Biocompatible Chitosan Hydrogels. J. Appl. Polym. Sci., 2008, 110:1059-1067
41. Xiaohong Hu, Jie Zhou, Nan Zhang, Huaping Tan, Changyou Gao*. Preparation and properties of an injectable scaffold of poly(lactic-co-glycolic acid) microparticles/chitosan hydrogel. Journal of the Mechanical Behavior of Biomedical Materials, 2008, 1:352-359.
授权的发明专利:
1. 胡小红,邱杰,张国俊,刘理,一种载药的角膜接触镜用水凝胶的制备方法。专利号:201110187260.0,授权日:2013.12.25 (CN 102344523 B)
2. 胡小红,张国俊,邱杰,一种水凝胶角膜接触镜药物载体。专利号:201210153382.2,授权日:2014.3.6(CN 102631711 B)
3. 胡小红,邱杰,张国俊,一种可交联聚合且含药物配体的壳聚糖衍生物。专利号:201210103847.3,授权日:2014.12.10 (CN102863553B)
4. 胡小红,陈频,马小涵,王昕,董岩,具有仿生特性的角膜接触镜药物载体及其制备方法。专利号:201410039173.4,授权日:2015.06.03
5. 胡小红,马小涵,多亚茹,张新燕,刘天宇,赵尧,蔡超杰,一种氧化石墨烯复合水凝胶药物载体。专利号:201310130242.8,授权日:2015.11.18
6. 胡小红,潘成斌,张新燕,多亚茹,陈秀霞,张元晟,一种可注射性氧化石墨烯/石墨烯复合水凝胶及其制备方法。专利号:201310189202.0. 授权日:2016.04.13
7. 胡小红,董岩,陈频,王昕,用于药物传递的隐形眼镜的表面改性方法。专利号:201410038271.6. 授权日:2016.04.13
8. 胡小红,王昕,陈频,张新燕,马小涵,董岩, 含聚合物胶束的水凝胶药物载体及其制备方法。专利号:201410559716.5授权日:2017.07.21
9. 胡小红,陈频,王昕,陈尚能,一种用于水凝胶药物载体制备的环境友好的表面改性方法。专利号:201510208653.3授权日:2017.10.10
10. 胡小红,王昕,陈频,高子喻,一种具有pH敏感特性环糊精纳米粒子复合电纺纤维的制备方法。申请号:201610843538.8 授权日:2019.04.23
11. 胡小红,王慧民,高子喻,庞娟,一种具有光响应的纳米载体及其制备方法,申请号:2018108125889 授权日:2020.7.10
12. 胡小红,王慧民,高子喻,庞娟,一种可功能化高分子光开关及其合成方法, 2018108119159 授权日:2020.9.15
13. 胡小红,庞娟,王昕,陈频,一种光控特性的水凝胶药物载体, 202010903193.7 授权日:2022.5.20
14. 胡小红,李新华,庞娟,王昕,陈频,一种具有pH指示功能的隐形眼镜的制备方法, 202210870288.2,授权日:2023.6.30
8. 联系方式
hxh@jit.edu.cn, 18913805386